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A Two-part, Randomised, Double-blind, Placebo-controlled Single and Multiple Ascending Dose Study to Assess Safety, Pharmacokinetics and Pharmacodynamics of Oral HTL0016878 in Healthy Younger Adult and Elderly Subjects With a Randomised, Open-label, Crossover Arm to Assess the Effect of Food on Bioavailability of Oral HTL0016878.

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Trial Profile

A Two-part, Randomised, Double-blind, Placebo-controlled Single and Multiple Ascending Dose Study to Assess Safety, Pharmacokinetics and Pharmacodynamics of Oral HTL0016878 in Healthy Younger Adult and Elderly Subjects With a Randomised, Open-label, Crossover Arm to Assess the Effect of Food on Bioavailability of Oral HTL0016878.

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 10 Apr 2024

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At a glance

  • Drugs HTL-0016878 (Primary)
  • Indications Alzheimer's disease
  • Focus Adverse reactions; First in man
  • Sponsors Heptares Therapeutics; Nxera Pharma; Sosei Heptares
  • Most Recent Events

    • 01 Apr 2024 According to a Nxera Pharma Co., Ltd. media release, Sosei Heptares name changed to Nxera Pharma Co., Ltd.
    • 27 Nov 2019 Status changed from recruiting to completed.
    • 22 Feb 2019 Planned End Date changed from 1 Sep 2018 to 1 Sep 2019.

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