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A Phase 2, Multi-Cohort Study to Investigate the Safety, Pharmacokinetics and Preliminary Antitumor Activity of the Anti-PD-1 Monoclonal Antibody BGB A317 in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable, Locally Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Carcinoma

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Trial Profile

A Phase 2, Multi-Cohort Study to Investigate the Safety, Pharmacokinetics and Preliminary Antitumor Activity of the Anti-PD-1 Monoclonal Antibody BGB A317 in Combination With Chemotherapy as First-Line Treatment in Adults With Inoperable, Locally Advanced or Metastatic Esophageal, Gastric, or Gastroesophageal Junction Carcinoma

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Tislelizumab (Primary) ; Capecitabine; Cisplatin; Fluorouracil; Oxaliplatin
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer; Squamous cell cancer
  • Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
  • Sponsors BeiGene

    • Most Recent Events

    • 29 Sep 2020 Status changed from active, no longer recruiting to completed.
    • 05 Aug 2020 Planned End Date changed from 30 Jun 2020 to 30 Aug 2020.
    • 19 Jun 2020 Results published in the Clinical Cancer Research

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