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A Phase I, unicentric, open and dose escalation clinical trial to evaluate the safety and the activity of the oncolytic adenovirus VCN-01 in patients with refractory retinoblastoma

Trial Profile

A Phase I, unicentric, open and dose escalation clinical trial to evaluate the safety and the activity of the oncolytic adenovirus VCN-01 in patients with refractory retinoblastoma

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 30 May 2025

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At a glance

  • Drugs VCN 01 (Primary) ; VCN 01 (Primary)
  • Indications Retinoblastoma
  • Focus Adverse reactions

Most Recent Events

  • 27 May 2025 According to Theriva Biologics media release, the data will be featured in a poster at the American Society of Clinical Oncology (ASCO) Annual Meeting, taking place in Chicago, IL from May 30-June 03, 2025.
  • 27 Aug 2024 Status changed from active, no longer recruiting to completed.
  • 13 Aug 2024 According to Theriva Biologics media release, the results form this trial were determined to be positive by the study Monitoring Committee. Discussions with key opinion leaders worldwide, as well as with regulatory agencies, are ongoing to refine our retinoblastoma clinical strategy.

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