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A Phase 1/2a, First-in-human, Oral Single and Multiple Dose-escalation, Randomized, Double-blinded, Placebo-controlled Study of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria to Evaluate Safety, Tolerability, Kinetics, and Pharmacodynamics

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Trial Profile

A Phase 1/2a, First-in-human, Oral Single and Multiple Dose-escalation, Randomized, Double-blinded, Placebo-controlled Study of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria to Evaluate Safety, Tolerability, Kinetics, and Pharmacodynamics

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs SYNB-1618 (Primary)
  • Indications Phenylketonuria
  • Focus Adverse reactions; Biomarker; First in man
  • Sponsors Synlogic

    • Most Recent Events

    • 22 Jul 2021 Results published in a Synlogic Media Release.
    • 22 Jul 2021 According to a Synlogic media release, data from this study was presented at Nature Metabolism and Communications.
    • 09 Jan 2020 According to a Synlogic media release, data from this study will be presented at an appropriate medical meeting in 2020.

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