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Phase II Study of the Combination of Blinatumomab and Ponatinib in Patients With Philadelphia Chromosome (Ph)-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia (ALL)

Trial Profile

Phase II Study of the Combination of Blinatumomab and Ponatinib in Patients With Philadelphia Chromosome (Ph)-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia (ALL)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 12 Feb 2025

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At a glance

  • Drugs Blinatumomab (Primary) ; Ponatinib (Primary) ; Cytarabine; Dexamethasone; Dexamethasone; Methotrexate
  • Indications Chronic myeloid leukaemia; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Therapeutic Use

Most Recent Events

  • 26 Feb 2024 Planned End Date changed from 30 Nov 2024 to 30 Nov 2025.
  • 26 Feb 2024 Planned primary completion date changed from 30 Nov 2024 to 30 Nov 2025.
  • 12 Dec 2023 Results(Between June 2018 and May 2023, n=62 pts) presented at the 65th American Society of Hematology Annual Meeting and Exposition

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