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A Phase 2, Multiple-Dose, Dose-Escalation Study to Evaluate the Safety and Efficacy of SPR001 in Adults With Classic Congenital Adrenal Hyperplasia (CAH)

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Trial Profile

A Phase 2, Multiple-Dose, Dose-Escalation Study to Evaluate the Safety and Efficacy of SPR001 in Adults With Classic Congenital Adrenal Hyperplasia (CAH)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Tildacerfont (Primary)
  • Indications Congenital adrenal hyperplasia
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Sponsors Spruce Biosciences
  • Most Recent Events

    • 21 Jun 2021 Results from two Phase 2 clinical studies (SPR001-201 and SPR001-202) presented in the Journal of Clinical Endocrinology and Metabolism.
    • 21 Jun 2021 Results published in Spruce Biosciences Media Release.
    • 19 Jun 2021 Results post hoc analyses from two open-label Phase 2 clinical trials (SPR001-201 and SPR001-202) assessing the safety and efficacy of tildacerfont in adult participants with 21OHD, published in the Journal of Clinical Endocrinology and Metabolism.

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