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A Phase 2B, Randomized, Double-Blind, Active-Comparator-Controlled, Dose-Ranging Clinical Trial to Evaluate the Safety, Tolerability, Antiretroviral Activity, and Pharmacokinetics of MK-8591 Given in Combination With Doravirine (DOR) and Lamivudine (3TC) in HIV-1-Infected Treatment-Naïve Adults

Trial Profile

A Phase 2B, Randomized, Double-Blind, Active-Comparator-Controlled, Dose-Ranging Clinical Trial to Evaluate the Safety, Tolerability, Antiretroviral Activity, and Pharmacokinetics of MK-8591 Given in Combination With Doravirine (DOR) and Lamivudine (3TC) in HIV-1-Infected Treatment-Naïve Adults

Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 07 Oct 2018

At a glance

  • Drugs Islatravir (Primary) ; Doravirine; Doravirine/lamivudine/tenofovir disoproxil fumarate; Lamivudine
  • Indications HIV-1 infections
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms DRIVE2Simplify
  • Sponsors Merck Sharp & Dohme
  • Most Recent Events

    • 07 Oct 2018 Results presented at the IDWeek 2018
    • 31 Aug 2018 Biomarkers information updated
    • 26 Apr 2018 Status changed from recruiting to active, no longer recruiting.
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