Randomised, Multicentre, Phase II Pilot Study to Assess the Efficacy and Safety of Treatment With FOLFIRI-aflibercept Compared to Initial Treatment With FOLFIRI-aflibercept (for 6 Cycles) Followed by Maintenance With 5FU-aflibercept, in an Elderly Population With Metastatic Colorectal Cancer (mCRC) After Failure of an Oxaliplatin-based Regimen
Latest Information Update: 05 Dec 2023
At a glance
- Drugs Aflibercept (Primary) ; Fluorouracil; Folinic acid; Irinotecan
- Indications Adenocarcinoma; Colon cancer; Colorectal cancer; Rectal cancer
- Focus Therapeutic Use
- Acronyms AFEMA
- 24 Oct 2023 Results assessing efficacy and safety of FOLFIRI-aflibercept Compared to Initial Treatment With FOLFIRI-aflibercept, presented at the 48th European Society for Medical Oncology Congress.
- 24 Oct 2023 Primary endpoint (Progression-free survival) has been met, according to results presented at the 48th European Society for Medical Oncology Congress.
- 12 Apr 2023 Status changed from active, no longer recruiting to completed.