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Combined Effects of SGLT2 Inhibition and GLP-1 Receptor Agonism on Food Intake, Body Weight and Central Satiety and Reward Circuits in Obese T2DM Patients

Trial Profile

Combined Effects of SGLT2 Inhibition and GLP-1 Receptor Agonism on Food Intake, Body Weight and Central Satiety and Reward Circuits in Obese T2DM Patients

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 08 Apr 2022

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At a glance

  • Drugs Dapagliflozin (Primary) ; Exenatide (Primary)
  • Indications Obesity; Type 2 diabetes mellitus
  • Focus Therapeutic Use
  • Acronyms DECREASE
  • Most Recent Events

    • 03 Feb 2022 Results investigating the separate and combined effects of dapagliflozin and exenatide on the CNS in participants with obesity and type 2 diabetes published in the Journal of Clinical Endocrinology and Metabolism
    • 01 Aug 2021 Results of prespecified secondary analysis published in the Diabetes, Obesity and Metabolism
    • 08 Jun 2021 Status changed from recruiting to completed.

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