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Prospective, Randomized Phase III Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%

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Trial Profile

Prospective, Randomized Phase III Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 02 Dec 2024

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At a glance

  • Drugs Travoprost (Primary) ; Timolol
  • Indications Ocular hypertension; Open-angle glaucoma
  • Focus Therapeutic Use
  • Sponsors Glaukos Corporation

    • Most Recent Events

    • 28 Nov 2024 Status changed from active, no longer recruiting to completed.
    • 14 Dec 2023 According to a Glaukos Corporation media release, based on Phase 3 pivotal trials (GC-010 and GC-012), the U.S. Food and Drug Administration (FDA) approved its New Drug Application (NDA) for a single administration per eye of iDose TR (travoprost intracameral implant) 75 mcg, a prostaglandin analog indicated for the reduction of intraocular pressure (IOP) in patients with ocular hypertension (OHT) or open-angle glaucoma (OAG).
    • 27 Jun 2023 Dose of Travoprost intraocular implant is decreased from 78 to 75 mcg.

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