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A Pilot Study of FOLFIRINOX in Combination With Neoadjuvant Radiation for Gastric and GE Junction Cancers

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Trial Profile

A Pilot Study of FOLFIRINOX in Combination With Neoadjuvant Radiation for Gastric and GE Junction Cancers

Status: Active, no longer recruiting
Phase of Trial: Phase I

Latest Information Update: 06 Oct 2022

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At a glance

  • Drugs Carboplatin (Primary) ; Fluorouracil (Primary) ; Folinic acid (Primary) ; Irinotecan (Primary) ; Oxaliplatin (Primary) ; Paclitaxel (Primary) ; Pegfilgrastim
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 07 Oct 2022 Planned End Date changed from 30 Jun 2023 to 1 Sep 2023.
    • 30 Jul 2021 Primary endpoint has been met. (The completion rate of chemotherapy in combination with chemoradiation), as per Results published in the Clinical Cancer Research
    • 30 Jul 2021 Results assesing relationship between ctDNA and clinical outcomes and feasiblity and rate of pCR for neoadjuvant FOLFIRINOX followed by chemoradiation, published in the Clinical Cancer Research
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