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A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study to Compare the Efficacy and Safety of Sotatercept (ACE-011) Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH)

Trial Profile

A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study to Compare the Efficacy and Safety of Sotatercept (ACE-011) Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 23 May 2025

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At a glance

  • Drugs Sotatercept (Primary)
  • Indications Pulmonary arterial hypertension
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms PULSAR
  • Sponsors Acceleron Pharma

Most Recent Events

  • 16 May 2025 According to an Merck Sharp and Dohme media release, company announced data from this trial on pulmonary arterial hypertension (PAH) to be presented at the American Thoracic Societys (ATS) 2025 International Conference in San Francisco from May 16-21.
  • 22 May 2024 Results of this study presented at the 120th International Conference of the American Thoracic Society
  • 30 Aug 2022 Results published in the European Respiratory Journal

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