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Phase I Study of Ex Vivo Expanded/Activated Gamma Delta T-cell Infusion Following Haploidentical Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide

Trial Profile

Phase I Study of Ex Vivo Expanded/Activated Gamma Delta T-cell Infusion Following Haploidentical Hematopoietic Stem Cell Transplantation and Post-transplant Cyclophosphamide

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 09 Apr 2026

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At a glance

  • Drugs INB-100 (Primary) ; Cyclophosphamide; Fludarabine
  • Indications Acute myeloid leukaemia; Chronic myeloid leukaemia; Haematological malignancies; Myelodysplastic syndromes; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions; First in man

Most Recent Events

  • 25 Mar 2026 Planned End Date changed from 1 Jan 2025 to 1 Jan 2028.
  • 25 Mar 2026 Planned primary completion date changed from 1 Jan 2024 to 1 Jan 2027.
  • 06 Nov 2025 According to an IN8bio media release, expanded phase 1 INB-100 trial to The James Comprehensive Cancer Center at The Ohio State University, supporting faster enrollment to complete the phase 1 expansion cohort.

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