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Phase II Study of CDK 4/6 Inhibitor, LEE011 (Ribociclib), in Combination With Adjuvant Endocrine Therapy at Varying Duration for ER-positive Breast Cancer (LEADER)

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Trial Profile

Phase II Study of CDK 4/6 Inhibitor, LEE011 (Ribociclib), in Combination With Adjuvant Endocrine Therapy at Varying Duration for ER-positive Breast Cancer (LEADER)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 03 Apr 2024

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At a glance

  • Drugs Ribociclib (Primary) ; Aromatase inhibitors
  • Indications Advanced breast cancer; Early breast cancer; HER2 negative breast cancer
  • Focus Therapeutic Use
  • Acronyms LEADER
  • Most Recent Events

    • 06 Dec 2023 According to a Natera media release, data from this study are being presented at the 2023 San Antonio Breast Cancer Symposium (SABCS).
    • 07 Dec 2022 According to a Natera media release, new clinical data on its personalized and tumor-informed molecular residual disease (MRD) test, Signatera, and its hereditary cancer test, Empower, will be presented at the 2022 San Antonio Breast Cancer Symposium (SABCS) in San Antonio, Texas.
    • 25 Oct 2021 Planned End Date changed from 1 Oct 2024 to 1 Oct 2026.

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