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Phase I/II, Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM14 in Combination with Irinotecan in Pretreated Patients with Selected Advanced Solid Tumors

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Trial Profile

Phase I/II, Multicenter, Open-label, Clinical and Pharmacokinetic Study of PM14 in Combination with Irinotecan in Pretreated Patients with Selected Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 09 Sep 2021

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At a glance

  • Drugs Ecubectedin (Primary) ; Irinotecan (Primary)
  • Indications Adenocarcinoma; Adrenocortical carcinoma; Biliary cancer; Bladder cancer; Breast cancer; Carcinoma; Cervical cancer; Endometrial cancer; Ewing's sarcoma; Fallopian tube cancer; Gastric cancer; Leiomyosarcoma; Liposarcoma; Liver cancer; Malignant-mesothelioma; Neuroendocrine tumours; Non-small cell lung cancer; Oesophageal cancer; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Prostate cancer; Renal cell carcinoma; Small cell lung cancer; Solid tumours; Synovial sarcoma
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors PharmaMar
  • Most Recent Events

    • 08 Jun 2021 Results (n=37) assessing safety, efficacy and pharmacokinetics of PM14 in patients with advanced solid tumors, presented at the 57th Annual Meeting of the American Society of Clinical Oncology.
    • 22 Sep 2017 New trial record

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