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A Randomised Double-blind (Sponsor Open), Placebo Controlled, Single Ascending Dose, First Time in Human Study in Participants With Mild to Moderate Asthma to Assess Safety, Tolerability, Immunogenicity, Pharmacokinetics and Pharmacodynamics of GSK3511294 Administered Subcutaneously

Trial Profile

A Randomised Double-blind (Sponsor Open), Placebo Controlled, Single Ascending Dose, First Time in Human Study in Participants With Mild to Moderate Asthma to Assess Safety, Tolerability, Immunogenicity, Pharmacokinetics and Pharmacodynamics of GSK3511294 Administered Subcutaneously

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Sep 2023

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At a glance

  • Drugs Depemokimab (Primary) ; Salbutamol
  • Indications Asthma
  • Focus Adverse reactions; First in man
  • Sponsors GlaxoSmithKline; GSK
  • Most Recent Events

    • 22 Jul 2021 Results assessing safety, tolerability, pharmacokinetics (PK) and effect on blood eosinophil counts, published in the British Journal of Clinical Pharmacology.
    • 10 Sep 2019 Status changed from active, no longer recruiting to completed.
    • 19 Apr 2019 Planned End Date changed from 24 Sep 2019 to 2 Aug 2019.
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