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Mechanisms Underlying Asthma Exacerbations Prevented and Persistent With Immune-Based Therapy: A Systems Approach Phase 2 (ICAC-30)

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Trial Profile

Mechanisms Underlying Asthma Exacerbations Prevented and Persistent With Immune-Based Therapy: A Systems Approach Phase 2 (ICAC-30)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 25 Jun 2024

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At a glance

  • Drugs Mepolizumab (Primary)
  • Indications Asthma
  • Focus Therapeutic Use
  • Acronyms MUPPITS-2

    • Most Recent Events

    • 22 May 2024 Results (n=290 in subgroups) assessing the efficacy of mepolizumab in urban children with exacerbation-prone asthma and greater than or equal to 150 blood eosinophils /microliter were presented at the 120th International Conference of the American Thoracic Society.
    • 22 May 2024 Results (n=53) of analysis of mechanisms of asthma exacerbations in the context of anti-IL5 treatment, an in-depth analysis of sputum eosinophil marker expression using mass cytometry presented at the 120th International Conference of the American Thoracic Society.
    • 27 Apr 2021 Status changed from active, no longer recruiting to completed.

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