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A Phase I Dose Escalation / Dose Expansion Study of NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy

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Trial Profile

A Phase I Dose Escalation / Dose Expansion Study of NBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 Therapy

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 25 Mar 2025

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At a glance

  • Drugs Hafnium oxide (Primary) ; Nivolumab; Pembrolizumab
  • Indications Bladder cancer; Cancer metastases; Cervical cancer; Gastric cancer; Head and neck cancer; Liver cancer; Liver metastases; Lung cancer; Malignant melanoma; Merkel cell carcinoma; Non-small cell lung cancer; Solid tumours; Squamous cell cancer; Triple negative breast cancer; Urogenital cancer
  • Focus Adverse reactions; First in man
  • Sponsors Nanobiotix

Most Recent Events

  • 20 Mar 2025 According to a Nanobiotix media release, data from the study to be presented at the 2025 European Lung Cancer Conference (ELCC).
  • 12 Nov 2024 According to a Nanobiotix media release, Initial Phase 1 dose escalation data from this study is expected in 1H 2025.
  • 12 Jun 2024 According to a Nanobiotix media release, company will host a virtual KOL (Key Opinion Leader) event Tuesday June 18, 2024 at 9:00-10:30AM EDT / 3:00-4:30PM CEST to discuss the Role of NBTXR3 and Immune Oncology in Advancing Head & Neck Cancer.

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