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A Randomized, Open-label, Multi-center Phase III Study of Durvalumab and Tremelimumab as First-line Treatment in Patients with advanced Hepatocellular Carcinoma (HIMALAYA)

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Trial Profile

A Randomized, Open-label, Multi-center Phase III Study of Durvalumab and Tremelimumab as First-line Treatment in Patients with advanced Hepatocellular Carcinoma (HIMALAYA)

Status: Active, no longer recruiting
Phase of Trial: Phase II/III

Latest Information Update: 22 Sep 2024

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At a glance

  • Drugs Durvalumab (Primary) ; Tremelimumab (Primary) ; Sorafenib
  • Indications Liver cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms HIMALAYA
  • Sponsors AstraZeneca
  • Most Recent Events

    • 16 Sep 2024 Results published in the Media Release
    • 16 Sep 2024 results from HIMALAYA will be presented at the European Society for Medical Oncology (ESMO) Congress 2024 in Barcelona, Spain (presentation 947MO).
    • 03 Sep 2024 According to an AstraZeneca media release, a mini-oral presentation featuring five-year OS data from an exploratory analysis of the HIMALAYA Phase III trial of STRIDE (Single Tremelimumab-actl Regular Interval Durvalumab) in patients with unresectable liver cancer who have not received prior systemic therapy and are not eligible for localized treatment.

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