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ARRO-CITO: (UMCC 2017.055) Phase Ib/II Single-Arm Multi-Center Study of IONIS-AR-2.5Rx, a Next Generation Androgen Receptor Antisense Oligonucleotide, in Combination With Enzalutamide in Metastatic Castration Resistant Prostate Cancer

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Trial Profile

ARRO-CITO: (UMCC 2017.055) Phase Ib/II Single-Arm Multi-Center Study of IONIS-AR-2.5Rx, a Next Generation Androgen Receptor Antisense Oligonucleotide, in Combination With Enzalutamide in Metastatic Castration Resistant Prostate Cancer

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 31 Jan 2024

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At a glance

  • Drugs Enzalutamide (Primary) ; IONIS AR 2.5Rx (Primary)
  • Indications Adenocarcinoma; Prostate cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ARRO-CITO
  • Most Recent Events

    • 23 Jan 2024 Study phase has been changed from 1/2 to 1. According to Clinical trial.gov record, The study was originally registered as a phase 1/ phase 2 study; however, the study was cancelled by the sponsor before opening the phase 2 portion.
    • 23 Jan 2023 Status changed from suspended to discontinued.
    • 17 Dec 2021 Status changed from recruiting to suspended. Reason the study was stopped: New patient enrollment will be temporarily suspended. Currently enrolled patients can continue on study treatment. This is not an IRB suspension.

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