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A Phase 3, Randomized, Double-Blind Study of Pembrolizumab Plus Ipilimumab vs Pembrolizumab Plus Placebo in Previously Untreated, Stage IV, Metastatic Non-small Cell Lung Cancer Subjects Whose Tumors Are PD-L1 Positive (TPS ≥ 50%) (KEYNOTE-598)

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Trial Profile

A Phase 3, Randomized, Double-Blind Study of Pembrolizumab Plus Ipilimumab vs Pembrolizumab Plus Placebo in Previously Untreated, Stage IV, Metastatic Non-small Cell Lung Cancer Subjects Whose Tumors Are PD-L1 Positive (TPS ≥ 50%) (KEYNOTE-598)

Status: Discontinued
Phase of Trial: Phase III

Latest Information Update: 13 Jun 2024

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At a glance

  • Drugs Ipilimumab (Primary) ; Pembrolizumab (Primary)
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms KEYNOTE-598
  • Sponsors Merck Sharp & Dohme Corp.

    • Most Recent Events

    • 19 Jan 2024 This trial has been completed in Italy (End Date: 07 Sep 2022).
    • 06 Mar 2023 This trial has been completed in Hungary (End Date: 07 Sep 2022), according to the European Clinical Trials Database record.
    • 24 Dec 2022 This trial has been completed in Poland (Date of the global end of the trial : 07-Sep-2022), according to European Clinical Trials Database record.

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