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A phase Ib/IIa pilot trial of the oral Hedgehog Signalling Inhibitor, Glasdegib, in Patients with sclerotic chronic graft-versus-host disease refractory to second-line treatment

Trial Profile

A phase Ib/IIa pilot trial of the oral Hedgehog Signalling Inhibitor, Glasdegib, in Patients with sclerotic chronic graft-versus-host disease refractory to second-line treatment

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 19 Dec 2019

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At a glance

  • Drugs Glasdegib (Primary)
  • Indications Graft-versus-host disease; Transplant rejection
  • Focus Adverse reactions
  • Most Recent Events

    • 16 Dec 2019 Planned End Date changed from 9 Jan 2022 to 9 Jan 2023.
    • 16 Dec 2019 Planned primary completion date changed from 9 Jan 2022 to 9 Jan 2023.
    • 14 Oct 2019 Planned number of patients changed from 24 to 21.
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