Trial Profile
A phase Ib/IIa pilot trial of the oral Hedgehog Signalling Inhibitor, Glasdegib, in Patients with sclerotic chronic graft-versus-host disease refractory to second-line treatment
Status:
Completed
Phase of Trial:
Phase I/II
Latest Information Update: 05 Mar 2024
Price :
$35
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At a glance
- Drugs Glasdegib (Primary)
- Indications Graft-versus-host disease
- Focus Adverse reactions
- Acronyms GETH trial
- 13 Dec 2022 Results from two clinical studies: NCT03415867 and NCT04111497 assessing safety and efficacy of glasdegib in adult patients with refractory scGVHD at data cutoff of 12-months presented at the 64th American Society of Hematology Annual Meeting and Exposition
- 21 Nov 2021 Status changed from active, no longer recruiting to completed.
- 17 Jun 2021 Results presented at the 26th Congress of the European Haematology Association