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Phase I, First-in-Human, Open-Label, Multiple-Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Activity of MS201408-0005A as Single Agent and Sequentially in Combinations With MS201408-0005C or MS201408-0005B in Subjects With Metastatic or Locally Advanced Unresectable Solid Tumors

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Trial Profile

Phase I, First-in-Human, Open-Label, Multiple-Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Activity of MS201408-0005A as Single Agent and Sequentially in Combinations With MS201408-0005C or MS201408-0005B in Subjects With Metastatic or Locally Advanced Unresectable Solid Tumors

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 11 Feb 2020

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At a glance

  • Drugs MS-201408-0005-A-EMD-Serono (Primary) ; MS-201408-0005B-EMD-Serono (Primary) ; MS-201408-0005C-EMD-Serono (Primary) ; MS-201408-0005C-EMD-Serono (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions; First in man
  • Sponsors EMD Serono Research & Development Institute

    • Most Recent Events

    • 10 Feb 2020 Status changed from completed to discontinued.
    • 20 Mar 2019 Status changed from active, no longer recruiting to completed.
    • 13 Nov 2018 Planned End Date changed from 3 Sep 2020 to 1 Feb 2019.

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