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A Phase 1/2 Open-Label, Dose-Escalation and Clinical Response Study of Quaratusugene Ozeplasmid in Combination With Osimertinib in Patients With Advanced, Metastatic EGFR-Mutant, Metastatic Non-Small Cell Lung Cancer

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A Phase 1/2 Open-Label, Dose-Escalation and Clinical Response Study of Quaratusugene Ozeplasmid in Combination With Osimertinib in Patients With Advanced, Metastatic EGFR-Mutant, Metastatic Non-Small Cell Lung Cancer

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 23 Oct 2024

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At a glance

  • Drugs Osimertinib (Primary) ; Quaratusugene ozeplasmid (Primary) ; Carboplatin; Cisplatin; Dexamethasone; Diphenhydramine; Paracetamol; Pemetrexed
  • Indications Non-small cell lung cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms Acclaim-1
  • Sponsors Genprex

    • Most Recent Events

    • 17 Oct 2024 The protocol has been amendment to change in study timeframe its primary endpoint.
    • 17 Oct 2024 Planned End Date changed from 1 Dec 2027 to 1 Mar 2029.
    • 17 Oct 2024 Planned primary completion date changed from 1 Dec 2026 to 1 Mar 2028.

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