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A first Phase 2b study to investigate the safety and efficacy of the optimal dose range of PQ912 in early AD patients

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Trial Profile

A first Phase 2b study to investigate the safety and efficacy of the optimal dose range of PQ912 in early AD patients

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 29 Aug 2019

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At a glance

  • Drugs Varoglutamstat (Primary)
  • Indications Alzheimer's disease
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Acronyms SAPHIR 2
  • Sponsors Vivoryon Therapeutics
  • Most Recent Events

    • 29 Aug 2019 According to a Vivoryon Therapeutics AG media release, trial initiation is anticipated in the first quarter of 2020 with the topline results expected in the second half of 2022.
    • 19 Jul 2019 Status changed from planning to recruiting, according to a Vivoryon company website.
    • 29 Nov 2018 According to a Probiodrug media release, presented the detailed study design of the Phase 2b core program of PQ-912 which incorporated the newest FDA and EMA draft guidance for early AD trials.

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