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A Phase 2A Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Varoglutamstat (PQ912) in Patients With Early Alzheimer's Disease With a Stage-Gate to Phase 2B (VIVA-MIND)

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A Phase 2A Randomized Double-Blind Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Varoglutamstat (PQ912) in Patients With Early Alzheimer's Disease With a Stage-Gate to Phase 2B (VIVA-MIND)

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 11 Dec 2024

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At a glance

  • Drugs Varoglutamstat (Primary)
  • Indications Alzheimer's disease; Mild cognitive impairment
  • Focus Adverse reactions; Pharmacokinetics; Proof of concept; Therapeutic Use
  • Acronyms VIVA-MIND
  • Sponsors Vivoryon Therapeutics

    • Most Recent Events

    • 09 Dec 2024 According to a Vivoryon Therapeutics media release, Primary endpoint(2A Primary safety: proportion of participants who experience any adverse event of interest (AE-I).) has been met.
    • 09 Dec 2024 According to a Vivoryon Therapeutics media release,Company will provide further detail on the topline VIVA-MIND data on December 10, 2024, in its Q3 financial results webcast.
    • 09 Dec 2024 According to a Vivoryon Therapeutics media release, company announced positive Phase 2 topline data from its U.S. VIVA-MIND study of varoglutamstat (PQ912), an investigational oral glutaminyl cyclase (QPCT/L) inhibitor, in early AD.

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