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Profiling and Reversing Metabolic Insufficiency in the Tumor Microenvironment in Advanced Melanoma: A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma

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Trial Profile

Profiling and Reversing Metabolic Insufficiency in the Tumor Microenvironment in Advanced Melanoma: A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 13 May 2025

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At a glance

  • Drugs Metformin (Primary) ; Pembrolizumab (Primary)
  • Indications Malignant melanoma
  • Focus Therapeutic Use

Most Recent Events

  • 06 May 2025 Planned End Date changed from 1 Dec 2028 to 1 Dec 2029.
  • 06 May 2025 Planned primary completion date changed from 1 Jan 2027 to 1 Jan 2028.
  • 06 May 2024 Planned End Date changed from 1 Dec 2027 to 1 Dec 2028.

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