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A Randomized, Double-blind, Placebo Controlled, Phase II Study of Everolimus in Combination With Exemestane in the Treatment of Chinese Postmenopausal Women With Estrogen Receptor Positive, HER-2 Negative, Locally Advanced, Recurrent, or Metastatic Breast Cancer After Recurrence or Progression on Prior Letrozole or Anastrozole

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Trial Profile

A Randomized, Double-blind, Placebo Controlled, Phase II Study of Everolimus in Combination With Exemestane in the Treatment of Chinese Postmenopausal Women With Estrogen Receptor Positive, HER-2 Negative, Locally Advanced, Recurrent, or Metastatic Breast Cancer After Recurrence or Progression on Prior Letrozole or Anastrozole

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 30 Jan 2024

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At a glance

  • Drugs Everolimus (Primary) ; Exemestane (Primary)
  • Indications Advanced breast cancer; HER2 negative breast cancer
  • Focus Therapeutic Use
  • Acronyms BOLERO-5
  • Sponsors Novartis; Novartis Pharmaceuticals
  • Most Recent Events

    • 17 Jun 2022 Status changed from active, no longer recruiting to completed.
    • 02 May 2022 Planned End Date changed from 29 Apr 2022 to 11 Nov 2022.
    • 17 Jun 2020 Planned End Date changed from 28 Apr 2022 to 29 Apr 2022.

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