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Phase II Study to Assess the Safety, Tolerability, and Target Engagement of AMX0035, a Fixed Combination of Sodium Phenylbutyrate and Tauroursodeoxycholic Acid for the Treatment of Alzheimer's Disease

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Trial Profile

Phase II Study to Assess the Safety, Tolerability, and Target Engagement of AMX0035, a Fixed Combination of Sodium Phenylbutyrate and Tauroursodeoxycholic Acid for the Treatment of Alzheimer's Disease

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 07 Jun 2022

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At a glance

  • Drugs Sodium phenylbutyrate/ursodoxicoltaurine (Primary)
  • Indications Alzheimer's disease
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms PEGASUS
  • Sponsors Amylyx Pharmaceuticals

    • Most Recent Events

    • 26 Apr 2022 Safety and tolerability results from CENTAUR, CENTAUR-OLE and PEGASUS studies, presented at the 74th Annual Meeting of the American Academy of Neurology 2022.
    • 04 Apr 2022 According to an Amylyx Pharmaceuticals media release, data from the trial was presented at the 2022 American Academy of Neurology Annual Meeting.
    • 02 Apr 2022 According to an Amylyx Pharmaceuticals media release, data from the study will be presented at 2022 American Academy of Neurology Annual Meeting.

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