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PhAse 1/2 StuDy of Modern ImmunotherApy in BCG-Unresponsive, BCG-RelaPsing, and High-Risk BCG-Naive Non-muscle Invasive UroThelial Carcinoma of the BLADDER

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Trial Profile

PhAse 1/2 StuDy of Modern ImmunotherApy in BCG-Unresponsive, BCG-RelaPsing, and High-Risk BCG-Naive Non-muscle Invasive UroThelial Carcinoma of the BLADDER

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 15 May 2023

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At a glance

  • Drugs BCG vaccine (Primary) ; Docetaxel (Primary) ; Durvalumab (Primary) ; Gemcitabine (Primary) ; Tremelimumab (Primary)
  • Indications Bladder cancer; Carcinoma; Urogenital cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms ADAPT-BLADDER

    • Most Recent Events

    • 11 Jan 2023 The treatment arms increased from 6 to 7. Planned patient number decreased from 186 to 55.
    • 11 Jan 2023 Planned End Date changed from 1 Dec 2023 to 31 Dec 2025.
    • 11 Jan 2023 Planned primary completion date changed from 1 Dec 2022 to 31 Dec 2024.
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