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GRAVITAS-119: A Single-Arm, Open-Label, Phase 1 Study of Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease

Trial Profile

GRAVITAS-119: A Single-Arm, Open-Label, Phase 1 Study of Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 15 Nov 2019

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At a glance

  • Drugs Itacitinib (Primary) ; Ciclosporin; Cyclophosphamide; Methotrexate; Mycophenolate mofetil; Tacrolimus
  • Indications Graft-versus-host disease
  • Focus Therapeutic Use
  • Acronyms GRAVITAS-119
  • Sponsors Incyte Corporation
  • Most Recent Events

    • 10 Oct 2019 Planned number of patients changed from 60 to 85.
    • 10 Oct 2019 Planned End Date changed from 1 Jan 2021 to 1 Jul 2021.
    • 10 Oct 2019 Planned primary completion date changed from 1 Feb 2020 to 1 Jul 2020.
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