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A Phase II Study of Lenvatinib, a Multi-targeted Tyrosine Kinase Inhibitor, Combined With Pembrolizumab (PD-1 Inhibitor) for the Treatment of Metastatic Gastroesophageal Cancer Patients Who Have Progressed on First or Subsequent Line Therapies

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Trial Profile

A Phase II Study of Lenvatinib, a Multi-targeted Tyrosine Kinase Inhibitor, Combined With Pembrolizumab (PD-1 Inhibitor) for the Treatment of Metastatic Gastroesophageal Cancer Patients Who Have Progressed on First or Subsequent Line Therapies

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 29 Mar 2024

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At a glance

  • Drugs Lenvatinib (Primary) ; Pembrolizumab (Primary)
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 28 Feb 2024 Status changed from suspended to completed.
    • 27 Jul 2023 Planned End Date changed from 1 Sep 2023 to 30 Sep 2023.
    • 06 Jun 2023 Primary endpoint (Overall Response Rate) has not been met, as per results presented at the 59th Annual Meeting of the American Society of Clinical Oncology.

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