A Phase Ib Study of the Combination of Venetoclax With Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia
Latest Information Update: 30 May 2024
At a glance
- Drugs Venetoclax (Primary) ; Cyclophosphamide; Cytarabine; Dexamethasone; Doxorubicin; Etoposide; Mercaptopurine; Methotrexate; Vincristine
- Indications Precursor B-cell lymphoblastic leukaemia-lymphoma; Precursor T-cell lymphoblastic leukaemia-lymphoma
- Focus Adverse reactions
- 27 May 2024 Planned End Date changed from 30 Apr 2025 to 30 Apr 2027.
- 27 May 2024 Planned primary completion date changed from 30 Apr 2024 to 30 Apr 2026.
- 12 Dec 2023 Results assessing responses after addition of VEN to hyper-CVD in newly diagnosed ALL, were presented at the 65th American Society of Hematology Annual Meeting and Exposition.