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A Phase 1 Cellular Immunotherapy Study of Intraventricularly Administered Autologous HER2-Targeted Chimeric Antigen Receptor (HER2-CAR) T Cells in Patients With Brain and/or Leptomeningeal Metastases From HER2 Positive Cancers

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Trial Profile

A Phase 1 Cellular Immunotherapy Study of Intraventricularly Administered Autologous HER2-Targeted Chimeric Antigen Receptor (HER2-CAR) T Cells in Patients With Brain and/or Leptomeningeal Metastases From HER2 Positive Cancers

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 05 Feb 2024

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At a glance

  • Drugs MB-103 (Primary)
  • Indications Brain metastases; Meningeal carcinomatosis
  • Focus Adverse reactions; First in man
  • Most Recent Events

    • 29 Jan 2024 Planned End Date changed from 31 Dec 2023 to 28 Feb 2025.
    • 29 Jan 2024 Planned primary completion date changed from 31 Dec 2023 to 28 Feb 2025.
    • 21 Sep 2023 Planned End Date changed from 31 Aug 2023 to 31 Dec 2023.

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