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A Paediatric Phase I/II Study Of Intermittent Dosing Of The Mek-1 Inhibitor Selumetinib In Children With Neurofibromatosis Type-1 And Inoperable Plexiform Neurofibroma And/Or Progressive Optic Pathway Glioma

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Trial Profile

A Paediatric Phase I/II Study Of Intermittent Dosing Of The Mek-1 Inhibitor Selumetinib In Children With Neurofibromatosis Type-1 And Inoperable Plexiform Neurofibroma And/Or Progressive Optic Pathway Glioma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 10 Apr 2024

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At a glance

  • Drugs Selumetinib (Primary)
  • Indications Neurofibromatosis 1; Optic nerve glioma; Plexiform neurofibroma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms INSPECT
  • Most Recent Events

    • 03 Apr 2024 Status changed from recruiting to completed.
    • 23 Feb 2023 Planned primary completion date changed from 1 Jan 2022 to 1 Aug 2023.
    • 11 Nov 2021 Planned primary completion date changed from 1 Aug 2021 to 1 Jan 2022.

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