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An Open-Label Phase 2 Proof-of-Concept Study in Patients With C3 Glomerulopathy (C3G) or Immune-Complex Membranoproliferative Glomerulonephritis (IC-MPGN) Treated With ACH-0144471

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Trial Profile

An Open-Label Phase 2 Proof-of-Concept Study in Patients With C3 Glomerulopathy (C3G) or Immune-Complex Membranoproliferative Glomerulonephritis (IC-MPGN) Treated With ACH-0144471

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 03 Nov 2023

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At a glance

  • Drugs Danicopan (Primary)
  • Indications Membranoproliferative glomerulonephritis
  • Focus Proof of concept; Therapeutic Use
  • Sponsors Achillion Pharmaceuticals; Alexion AstraZeneca Rare Disease
  • Most Recent Events

    • 09 Aug 2022 Status changed from completed to discontinued.
    • 07 Mar 2022 Inclusion criteria has been updated to remove the upper age limit of 65 years.
    • 18 Oct 2021 Inclusion criteria has been updated to decrease the lower age limit of subjects from 17 years to 12 years.

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