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A PHASE 1B/2 STUDY TO EVALUATE SAFETY AND ANTI TUMOR ACTIVITY OF AVELUMAB IN COMBINATION WITH THE POLY(ADENOSINE DIPHOSPHATE [ADP]-RIBOSE) POLYMERASE (PARP) INHIBITOR TALAZOPARIB IN PATIENTS WITH LOCALLY ADVANCED OR METASTATIC SOLID TUMORS

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A PHASE 1B/2 STUDY TO EVALUATE SAFETY AND ANTI TUMOR ACTIVITY OF AVELUMAB IN COMBINATION WITH THE POLY(ADENOSINE DIPHOSPHATE [ADP]-RIBOSE) POLYMERASE (PARP) INHIBITOR TALAZOPARIB IN PATIENTS WITH LOCALLY ADVANCED OR METASTATIC SOLID TUMORS

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 15 Oct 2023

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At a glance

  • Drugs Avelumab (Primary) ; Talazoparib (Primary)
  • Indications Advanced breast cancer; Carcinoma; Non-small cell lung cancer; Ovarian cancer; Prostate cancer; Solid tumours; Triple negative breast cancer; Urogenital cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms JAVELIN PARP MEDLEY
  • Sponsors Pfizer

    • Most Recent Events

    • 17 May 2023 Status changed from completed to discontinued.
    • 18 Jan 2023 Status changed from active, no longer recruiting to completed.
    • 08 Jan 2023 This trial has been completed in Belgium (End Date: 4 Jan 2023) according to European Clinical Trials Database record.

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