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A Randomized, Double-blind, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenously Administered Andexanet After Dosing to Steady-State With Oral Betrixaban in Healthy Subjects

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A Randomized, Double-blind, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Intravenously Administered Andexanet After Dosing to Steady-State With Oral Betrixaban in Healthy Subjects

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Andexanet alfa (Primary) ; Betrixaban (Primary)
  • Indications Haemorrhage; Venous thromboembolism
  • Focus Therapeutic Use
  • Sponsors Portola Pharmaceuticals

    • Most Recent Events

    • 07 Apr 2020 Status changed from recruiting to discontinued.
    • 06 Jun 2018 Planned End Date changed from 1 May 2018 to 1 Sep 2018.
    • 06 Jun 2018 Planned primary completion date changed from 1 May 2018 to 1 Sep 2018.

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