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A Pilot Trial of Adriamycin, Pembrolizumab, Vinblastine, and Dacarbazine (APVD) for Patients With Untreated Classical Hodgkin Lymphoma

Trial Profile

A Pilot Trial of Adriamycin, Pembrolizumab, Vinblastine, and Dacarbazine (APVD) for Patients With Untreated Classical Hodgkin Lymphoma

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 11 Jan 2025

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At a glance

  • Drugs Dacarbazine (Primary) ; Doxorubicin (Primary) ; Pembrolizumab (Primary) ; Vinblastine (Primary)
  • Indications Hodgkin's disease
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 10 Dec 2024 Results assessing overall rates of potential delayed irAEs, as defined below, in our cohort of 50 patients treated with pembrolizumab and AVD (APVD), presented at the 66th American Society of Hematology Annual Meeting and Exposition.
  • 10 Dec 2024 Results assessing updated clinical data full 50-patient study including interim and end of treatment (EOT) MRD testing by PhasED-Seq, presented at the 66th American Society of Hematology Annual Meeting and Exposition.
  • 12 Dec 2023 Results(n=50) presented at the 65th American Society of Hematology Annual Meeting and Exposition

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