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Pilot Study Of Redirected Autologous T Cells Engineered To Contain an Anti-BCMA scFv Coupled To TCRζ And 4-1BB Signaling Domains in Patients With Relapsed and/or Refractory Multiple Myeloma

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Trial Profile

Pilot Study Of Redirected Autologous T Cells Engineered To Contain an Anti-BCMA scFv Coupled To TCRζ And 4-1BB Signaling Domains in Patients With Relapsed and/or Refractory Multiple Myeloma

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 31 Mar 2023

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At a glance

  • Drugs MTV-273 (Primary) ; Cyclophosphamide
  • Indications Multiple myeloma
  • Focus Adverse reactions
  • Most Recent Events

    • 03 Aug 2020 Status changed from active, no longer recruiting to completed.
    • 06 May 2020 The event date Sep 23, 2016 has been taken from NCT based on the change in planned patient number from 15 to 27.
    • 10 Dec 2019 Results assessing Safety and Efficacy of B-Cell Maturation Antigen (BCMA)-Specific Chimeric Antigen Receptor T Cells (CART-BCMA) with Cyclophosphamide Conditioning for Refractory Multiple Myeloma presented at the 61st Annual Meeting and Exposition of the American Society of Hematology

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