An Open-Label, Multi-Drug, Biomarker-Directed, Multi-Centre Phase II Umbrella Study in Patients With Non-Small Cell Lung Cancer, Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy (HUDSON)
Latest Information Update: 30 Oct 2025
At a glance
- Drugs Cediranib (Primary) ; Ceralasertib (Primary) ; Danvatirsen (Primary) ; Durvalumab (Primary) ; Olaparib (Primary) ; Oleclumab (Primary) ; Trastuzumab-deruxtecan (Primary) ; Vistusertib (Primary)
- Indications Adenocarcinoma; Non-small cell lung cancer; Squamous cell cancer
- Focus Biomarker; Therapeutic Use
- Acronyms HUDSON
- Sponsors AstraZeneca; AstraZeneca AB
Most Recent Events
- 27 Oct 2025 The protocol has been amended to addition in treatment arm size and change in study time frame for primary endpoint.
- 27 Dec 2024 Planned End Date changed from 26 Sep 2024 to 11 Sep 2026.
- 27 Dec 2024 Planned primary completion date changed from 26 Sep 2024 to 11 Sep 2026.