Trial Profile

A Phase Ib/II, Open-Label, Multicenter, Randomized Umbrella Study Evaluating The Efficacy And Safety Of Multiple Immunotherapy-Based Treatment Combinations In Patients With Metastatic Non-Small Cell Lung Cancer (Morpheus-Lung)

Status: Completed

Phase of Trial: Phase I/II

Latest Information Update: 19 Dec 2025

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At a glance

Drugs Atezolizumab (Primary) ; Bevacizumab (Primary) ; Carboplatin (Primary) ; Cibisatamab (Primary) ; Ciforadenant (Primary) ; Cobimetinib (Primary) ; Docetaxel (Primary) ; Evolocumab (Primary) ; Gemcitabine (Primary) ; Ipatasertib (Primary) ; Linagliptin (Primary) ; Pemetrexed (Primary) ; Sacituzumab govitecan (Primary) ; Tocilizumab
Indications Carcinoma; Non-small cell lung cancer; Squamous cell cancer
Focus Adverse reactions; Proof of concept; Therapeutic Use
Acronyms MORPHEUS; Morpheus Lung; MORPHEUS-NSCLC
Sponsors Genentech; Roche

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