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DAPAMAAST: A Double-blind, Randomized, Phase IV, Mechanistic, Placebo-controlled, Cross-over, Single-center Study to Evaluate the Effects of 5 Weeks Dapagliflozin Treatment on Insulin Sensitivity in Skeletal Muscle in Type 2 Diabetes Mellitus Patients

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Trial Profile

DAPAMAAST: A Double-blind, Randomized, Phase IV, Mechanistic, Placebo-controlled, Cross-over, Single-center Study to Evaluate the Effects of 5 Weeks Dapagliflozin Treatment on Insulin Sensitivity in Skeletal Muscle in Type 2 Diabetes Mellitus Patients

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 07 Nov 2022

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At a glance

  • Drugs Dapagliflozin (Primary)
  • Indications Type 2 diabetes mellitus
  • Focus Pharmacodynamics
  • Acronyms DAPAMAAST
  • Sponsors AstraZeneca

    • Most Recent Events

    • 23 Sep 2022 Results assessing the effects of 5 weeks of dapagliflozin treatment on skeletal muscle fat metabolism in type 2 diabetes patients, presented at the 58th Annual Meeting of the European Association for the Study of Diabetes.
    • 15 Apr 2021 Results published in the Diabetes Care
    • 25 Sep 2020 Results assessing effects of dapagliflozin (DAPA) on insulin sensitivity, 24h energy metabolism and skeletal muscle mitochondrial function in patients with type 2 diabetes, presented at the 56th Annual Meeting of the European Association for the Study of Diabetes.
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