Bone Response After Luteinizing Hormone-releasing Hormone Analogue and Enzalutamide +/- Zoledronic Acid in Prostate Cancer Patients With Hormone Sensitive Metastatic Bone Disease: a Prospective, Phase II, Randomized, Multicenter Study
Latest Information Update: 11 Mar 2026
At a glance
- Drugs Enzalutamide (Primary) ; LHRH receptor antagonists; Zoledronic acid
- Indications Bone metastases; Carcinoma; Prostate cancer
- Focus Therapeutic Use
- Acronyms BonEnza
Most Recent Events
- 01 Mar 2026 Primary endpoint has not been met. (Evaluation of change in bone response after 6 and 12 months of treatment compared to baseline), according to results published in the Prostate Cancer and Prostatic Diseases.
- 01 Mar 2026 Results assessing efficacy of zoledronic acid published in the Prostate Cancer and Prostatic Diseases.
- 01 Aug 2024 Status changed from recruiting to completed.