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A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Dose Finding Study of ISIS 703802 (AKCEA-ANGPTL3-LRx) Administered Subcutaneously to Subjects With Hypertriglyceridemia, Type 2 Diabetes Mellitus (T2DM), and Nonalcoholic Fatty Liver Disease (NAFLD)

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Dose Finding Study of ISIS 703802 (AKCEA-ANGPTL3-LRx) Administered Subcutaneously to Subjects With Hypertriglyceridemia, Type 2 Diabetes Mellitus (T2DM), and Nonalcoholic Fatty Liver Disease (NAFLD)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 17 Sep 2021

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At a glance

  • Drugs Vupanorsen (Primary)
  • Indications Fatty liver; Hypertriglyceridaemia; Non-alcoholic fatty liver disease; Type 2 diabetes mellitus
  • Focus Therapeutic Use
  • Sponsors Akcea Therapeutics; Ionis Pharmaceuticals
  • Most Recent Events

    • 29 Aug 2020 According to an Akcea Therapeutics media release, data from this Phase 2 clinical trial were presented in an online Late Breaking Clinical Trial Session at the ESC Congress 2020, the annual meeting for the European Society of Cardiology.
    • 29 Aug 2020 Results presented in an Akcea Therapeutics media release.
    • 29 Aug 2020 Results published in the European Heart Journal
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