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A Phase 2 Study of Olaparib Monotherapy in Metastatic Breast Cancer Patients With Germline or Somatic Mutations in DNA Repair Genes (Olaparib Expanded)

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A Phase 2 Study of Olaparib Monotherapy in Metastatic Breast Cancer Patients With Germline or Somatic Mutations in DNA Repair Genes (Olaparib Expanded)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 05 Jul 2024

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At a glance

  • Drugs Olaparib (Primary)
  • Indications Advanced breast cancer; HER2 negative breast cancer; HER2 positive breast cancer; Male breast cancer; Triple negative breast cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 04 Jun 2024 Results (n=19) of the expansion cohorts for additional pts with gPALB2(Cohort 1a) or sBRCA (Cohort 2a) mutations, presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 16 Feb 2024 Planned primary completion date changed from 30 Dec 2023 to 30 Jul 2024.
    • 16 Feb 2024 Status changed from recruiting to active, no longer recruiting.

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