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An Open-Label, Multicenter, Phase 1/2 Study of RP1 as a Single Agent and in Combination With PD1 Blockade in Patients With Solid Tumors

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Trial Profile

An Open-Label, Multicenter, Phase 1/2 Study of RP1 as a Single Agent and in Combination With PD1 Blockade in Patients With Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 30 Dec 2024

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At a glance

  • Drugs Nivolumab (Primary) ; Vusolimogene oderparepvec (Primary)
  • Indications Basal cell cancer; Bladder cancer; Carcinoma; Haemangiosarcoma; Head and neck cancer; Malignant melanoma; Merkel cell carcinoma; Non-small cell lung cancer; Skin cancer; Solid tumours; Squamous cell cancer; Urogenital cancer; Uveal melanoma
  • Focus Adverse reactions; First in man; Registrational; Therapeutic Use
  • Acronyms IGNYTE
  • Sponsors Replimune

    • Most Recent Events

    • 27 Dec 2024 Planned number of patients changed from 300 to 340.
    • 27 Dec 2024 Planned End Date changed from 1 Nov 2024 to 1 Jun 2025.
    • 27 Dec 2024 Planned primary completion date changed from 1 Nov 2024 to 1 Jun 2025.

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