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An Open-Label, Multicenter, Phase 1/2 Study of RP1 as a Single Agent and in Combination With PD1 Blockade in Patients With Solid Tumors

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Trial Profile

An Open-Label, Multicenter, Phase 1/2 Study of RP1 as a Single Agent and in Combination With PD1 Blockade in Patients With Solid Tumors

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 08 Jun 2025

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At a glance

  • Drugs Nivolumab (Primary) ; Vusolimogene oderparepvec (Primary)
  • Indications Basal cell cancer; Bladder cancer; Carcinoma; Haemangiosarcoma; Head and neck cancer; Malignant melanoma; Merkel cell carcinoma; Non-small cell lung cancer; Skin cancer; Solid tumours; Squamous cell cancer; Urogenital cancer; Uveal melanoma
  • Focus Adverse reactions; First in man; Registrational; Therapeutic Use
  • Acronyms IGNYTE
  • Sponsors Replimune

Most Recent Events

  • 01 Jun 2025 Results presented in a Replimune media release
  • 01 Jun 2025 According to a Replimune media release, data from this trial presented in a poster presentation highlighting data updates for RP1 (vusolimogene oderparepvec) at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting taking place May 30-June 3 in Chicago.
  • 22 May 2025 According to a Replimune media release, data from this study will be presented at American Society of Clinical Oncology (ASCO) 2025 Annual Meeting being held May 30-June 3, 2025.

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