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Interest of iRECIST Radiological Assessment for Disease Control Rate (DCR) for Evaluation of Patients With Metastatic Colorectal Cancer dMMR and/or MSI Treated With Nivolumab and Ipilimumab. A GERCOR Open-label Phase II Study NIPICOL C17-01

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Interest of iRECIST Radiological Assessment for Disease Control Rate (DCR) for Evaluation of Patients With Metastatic Colorectal Cancer dMMR and/or MSI Treated With Nivolumab and Ipilimumab. A GERCOR Open-label Phase II Study NIPICOL C17-01

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 03 Jan 2025

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At a glance

  • Drugs Ipilimumab (Primary) ; Nivolumab (Primary)
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms GERCOR NIPICOL; NIPICOL

    • Most Recent Events

    • 01 Jun 2023 Results (n=116 , of the NIPICOL phase II trial and the IMMUNOMSI prospective cohort) assessing Prediction of Response to Immune Checkpoint Blockade in Patients with Metastatic Colorectal Cancer with Microsatellite Instability published in the Annals of Oncology
    • 22 Jan 2022 Results assessing the efficacy data with 16 months of additional follow-up since the primary analysis, presented at the 2022 Gastrointestinal Cancers Symposium.
    • 13 May 2021 Results of a post-hoc analysis assessing performance of new generation sequencing to identify microsatellite instability in colorectal cancer ; using samples from clinical trials NCT02840604 and NCT033501260 and two other clinical studies published in the Gastroenterology

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